I really wonder how you should raise kids to make them turn out like the main characters of Mitsudomoe. They all have funny personalities, one's more original than the other but definitly good enough to make you laugh.
The story's good but it still just a school anime. It's the combination of the teacher, nurse and students wich makes the plot so good.
I don't think I've ever seen a series with more misunderstandings and it's hilarious.
The art is really fitting. Especially some effects. The opening's done quite good aswell.
Mitsudomoe is really enjoyable. It wouldn't be the first anime I'd recommend but I would eventually. Some of the running gags are just so good.