One night, Kazuki Muto jumps in to try to save what he thinks is a girl in distress from a monster and instead gets impaled through the heart. The girl, Tokiko, is actually an alchemic warrior with a Busou Renkin, name of Valkerie Skirt, with the mission to exterminate Homunculi. She implants the only other successful work of alchemy than the Homunculus, the Kakugane, to take the place of Kazuki's heart. The Kakugane resonates with his fighting spirit and forms a Busou Renkin (in his case a spear) so he can fight the Homunculus monsters who prey on humans. Kazuki joins with Tokiko to battle with the Homunculi and protect his friends and his sister Mahiro.
Buso Renkin brings a new look about Alchemy you never thought possible. Aside the standard Humunculi (Full Metal Alchemist). It never lets up from the fights, drama, and angst the main characters have towards each other. Unlikely teams, as well as bizare turns of events here and there, and one thing that I always look for, but always miss no matter how many times I see it. It gives Supernatural genre/theme a new level of entertainment and meaning. One thing I didnt like is how Papillon dressed UGH*shivers*