Moritaka Mashiro and Akito Takagi are pretty much foils of each other. Mashiro, an average 9th grade student but talented artist, and Takagi, an overall advanced 9th grader and aspiring writer. After great convincing, Takagi convinces Mashiro to join him in becoming the greatest mangakas Japan has ever seen. Takagi, with his gift of writing, hopes to become a successful mangaka, and Mashiro, with his gift of art, hopes to marry the girl of his dreams, Azuki Miho.
Basically a mangaka decided to write a manga about mangakas. I knw it sounds stupid but it really brings light to what they go through to bring manga to our doorsteps (Dis ain't a joke folks). It's really interesting and i highly recommend you watch it, especially if you are bored of all those cliche anime settings.